Family members say Bob Barlow died of cancer Monday.
Barlow also had an uncommon form of Lou Gehrig's disease, also known as ALS.
Barlow's disease progressed more slowly than most ALS patients.
The neuromuscular disease is almost always fatal.
More than a decade ago, Barlow and his many family members founded the MDA Great Walk.
Walkers at the Warner Park event have helped raise thousands of dollars for research into Lou Gehrig's disease.
Also for more than a decade, Bob Barlow and his family volunteered to help make the Jerry Lewis MDA Labor Day Telethon on Channel 27 a success.